13-01811. Carbocloral [Archived]

Nomenclature

CAS number: 541-79-7
(2,2,2-Trichloro-1-hydroxyethyl)carbamic acid ethyl ester; ethyl (2,2,2-trichloro-1-hydroxyethyl)carbamate; chloral-urethane; CI-336; HY-185; Ural; Uraline; Uralium.
C5H8Cl3NO3; mol wt 236.48.
C 25.39%, H 3.41%, Cl 44.98%, N 5.92%, O 20.30%.
Cl3CCH(OH)NHCOOC2H5.

Description and references

Prepd from chloral and urethane in the presence of HCl: Bischoff, Ber. 7, 628 (1874).

Properties

Crystalline powder, mp ≈103° with partial decompn. Practically insol in water; freely sol in alcohol, ether.

Therapeutic Category

Hypnotic.

Keywords

Sedative/Hypnotic; Chloral Derivatives

Status

This monograph has been retired and is no longer subject to revision or update.