13-02213. Chlorthenoxazin(e) [Archived]

Nomenclature

CAS number: 132-89-8
2-(2-Chloroethyl)-2,3-dihydro-4H-1,3-benzoxazin-4-one; 2-(β-chloroethyl)-2,3-dihydro-4-oxo-(benzo-1,3-oxazine); 4-oxo-2-(β-chloroethyl)-2,3-dihydrobenzo-1,3-oxazine; 2-(β-chloroethyl)-2,3-dihydro-4-keto-(benzo-1,3-oxazine); AP-67; Valtorin (Boehringer, Ing.); Piroxina; Ossazone; Reumagrip; Ossipirina; Apirazin; Valmorin (Roerig).
C10H10ClNO2; mol wt 211.64.
C 56.75%, H 4.76%, Cl 16.75%, N 6.62%, O 15.12%.

Description and references

Prepn: Ohnacker, US 2943087 (1960 to Thomae).

Chemical structure

Properties

Crystals from ethanol, mp 146-147° (dec). Sol in chloroform. uv max (chloroform): 297.5 nm. Ingredient of Trigatan, Fiobrol.

Therapeutic Category

Antipyretic; analgesic.

Keywords

Analgesic (Non-Narcotic); Antipyretic

Status

This monograph has been retired and is no longer subject to revision or update.