13-03249. Dimethoxanate [Archived]

Nomenclature

CAS number: 477-93-0
10H-Phenothiazine-10-carboxylic acid 2-[2-(dimethylamino)ethoxy]ethyl ester; β-dimethylaminoethoxyethyl phenothiazine-10-carboxylate; Tussidin; Cotrane (Midy).
C19H22N2O3S; mol wt 358.45.
C 63.66%, H 6.19%, N 7.82%, O 13.39%, S 8.95%.

Description and references

Prepn: von Seeman, US 2778824 (1957 to American Home Prod.).

Chemical structure

Derivative

Hydrochloride.
C19H22N2O3S.HCl; mol wt 394.92.
C 57.78%, H 5.87%, N 7.09%, O 12.15%, S 8.12%, Cl 8.98%.

Properties

Crystals from anhydr acetone or methanol + ether, mp 161-163° (dec).
Ingredient of Cothera Syrup.

Therapeutic Category

Antitussive.

Keywords

Antitussive

Status

This monograph has been retired and is no longer subject to revision or update.