13-03239. Dimethazan [Archived]

Nomenclature

CAS number: 519-30-2
7-[2-(Dimethylamino)ethyl]-3,7-dihydro-1,3-dimethyl-1H-purine-2,6-dione; 7-(2-dimethylaminoethyl)theophylline; 1,3-dimethyl-7-(2-dimethylaminoethyl)xanthine; Elidin (Endo).
C11H17N5O2; mol wt 251.28.
C 52.58%, H 6.82%, N 27.87%, O 12.73%.

Description and references

Prepn from theophylline and dimethyl-2-chloroethylamine: Moussalli et al., GB 669070 (1952), C.A. 47, 5435i (1953); Klosa, Arch. Pharm. 288, 301 (1955). Pharmacology: Balatre, Merlen, Therapie 11, 1146 (1956); Yago, Jpn. Circ. J. 26, 407 (1962).

Chemical structure

Properties

Solid, mp 95°.

Derivative

Hydrochloride.
C11H17N5O2.HCl; mol wt 287.75.
C 45.91%, H 6.31%, N 24.34%, O 11.12%, Cl 12.32%.

Properties

mp 260°.

Therapeutic Category

Antidepressant.

Keywords

Antidepressant; Bicyclics

Status

This monograph has been retired and is no longer subject to revision or update.