Nomenclature
CAS number: 9001-72-3
Description and references
A proteolytic enzyme (proteinase, endopeptidase).
Partial purification and characterization: Grant, Robbins, J. Am. Chem. Soc. 78, 5888 (1956).
Isoln from hog or beef pancreas: eidem, US 2871165 (1959 to Armour).
Properties
Insol in water, sol in a 60% aq alcohol soln at
25°. Maintains proteolytic activity in aq solns of pH 4.7 at 25°
for 8 hrs. Incapable of clotting blood plasma, but clots milk. The
proteolytic activity upon urea-denatured hemoglobin and upon acetyl-1-tyrosine
ethyl ester is such that the ratio of its hemoglobin to ATEE activity
is at least 150.Status
This monograph has been retired and is no longer subject
to revision or update.