13-07095. Paraflutizide [Archived]

Nomenclature

CAS number: 1580-83-2
6-Chloro-3-[(4-Fluorophenyl)methyl]-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide; 1,1-dioxo-3-(p-fluorophenylmethyl)-3,4-dihydro-6-chloro-1,2,4-benzothiadiazine-7-sulfonamide; LD-3612.
C14H13ClFN3O4S2; mol wt 405.85.
C 41.43%, H 3.23%, Cl 8.74%, F 4.68%, N 10.35%, O 15.77%, S 15.80%.

Description and references

Prepn: BE 620829 (1962 to Lab. Dausse), C.A. 58, 12585g (1963), corresponds to GB 961641; FR M1374 (1962 to Lab. Dausse), C.A. 58, 2462c (1963). Synthesis: J. Klosa, J. Prakt. Chem. 33, 298 (1966).

Chemical structure

Properties

Crystals from 50% alcohol, mp 238-240°.

Therapeutic Category

Diuretic.

Keywords

Antihypertensive; Thiazides and Analogs; Diuretic; Thiazides and Analogs

Status

This monograph has been retired and is no longer subject to revision or update.