13-07301. Phenesterine [Archived]

Nomenclature

CAS number: 3546-10-9
(3β)-Cholest-5-en-3-ol 4-[bis(2-chloroethyl)amino]benzeneacetate; p-[bis(2-chloroethyl)amino]phenylacetic acid cholesterol ester; cholesteryl p-bis(2-chloroethyl)aminophenylacetate; fenesterin.
C39H59Cl2NO2; mol wt 644.80.
C 72.65%, H 9.22%, Cl 11.00%, N 2.17%, O 4.96%.

Description and references

Prepd from p-bis(2-chloroethyl)aminophenylacetic acid chloride and cholesterol: Shkodinskaya et al., Zh. Obshch. Khim. 32, 959 (1962), C.A. 58, 2502h (1963).

Chemical structure

Properties

Crystals, mp 90-90.5°. [α]D 13.7°.

Therapeutic Category

Antineoplastic.

Keywords

Antineoplastic; Alkylating Agents; Nitrogen Mustards

Status

This monograph has been retired and is no longer subject to revision or update.