13-07320. Phenobutiodil [Archived]

Nomenclature

CAS number: 554-24-5
2-(2,4,6-Triiodophenoxy)butanoic acid; 2-(2,4,6-triiodophenoxy)butyric acid; α-(2,4,6-triiodophenoxy)butyric acid; 1-(2,4,6-triiodophenoxy)propanecarboxylic acid; 4114 Th; Baygnostil; Vésipaque (Warner-Lambert).
C10H9I3O3; mol wt 557.89.
C 21.53%, H 1.63%, I 68.24%, O 8.60%.

Description and references

Prepn: Redel et al., Bull. Soc. Chim. Fr. 1954, 342; Redel, Maillard, US 2796432 (1957 to Chimie et Atomistique). Pharmacology: H. Bekker et al., Pharmazie 27, 411 (1972).

Chemical structure

Properties

Crystals from ether + petr ether, mp 124-125°. LD50 in mice (mg/kg): 1800 orally; 265 i.v. (Bekker).

Therapeutic Category

Diagnostic aid (radiopaque medium‐cholecystographic).

Keywords

Diagnostic Aid (Radiopaque Medium)

Status

This monograph has been retired and is no longer subject to revision or update.