13-07923. Propipocaine [Archived]

Nomenclature

CAS number: 3670-68-6
3-(1-Piperidinyl)-1-(4-propoxyphenyl)-1-propanone; 3-piperidino-4′-propoxypropiophenone; β-piperidinoethyl 4-propoxyphenyl ketone; 4-n-propoxy-β-(1-piperidyl)propiophenone; 4-propoxyphenyl piperidine ethyl ketone.
C17H25NO2; mol wt 275.39.
C 74.14%, H 9.15%, N 5.09%, O 11.62%.

Description and references

Prepd from p-propoxyacetophenone by condensation with formaldehyde and piperidine HCl: Profft, Chem. Tech. (Leipzig) 4, 241 (1952), C.A. 47, 10531 (1953).

Chemical structure

Derivative

Hydrochloride.

Nomenclature

CAS number: 1155-49-3
Falicain; Urocomb (Jenapharm).
C17H25NO2.HCl; mol wt 311.85.
C 65.47%, H 8.40%, N 4.49%, O 10.26%, Cl 11.37%.

Properties

Crystals, mp 166°. Sol in water, alcohol, acetone. Phenol coefficient 3.6. Aq solns should not be sterilized by autoclaving.

Therapeutic Category

Anesthetic (local).

Status

This monograph has been retired and is no longer subject to revision or update.