13-09749. Trifenmorph [Archived]

Nomenclature

CAS number: 1420-06-0
4-(Triphenylmethyl)morpholine; 4-tritylmorpholine; WL-8008; Frescon (Shell).
C23H23NO; mol wt 329.43.
C 83.86%, H 7.04%, N 4.25%, O 4.86%.

Description and references

Prepn: Adams et al., US 3577413 (1971 to Shell). Lab tests as molluscicide: Webbe, Sturrock, Ann. Trop. Med. Parasitol. 58, 234 (1964); C.A. 61, 15286g (1964). Field trials and toxicity: Boyce et al., Nature 210, 1140 (1966). Degradn: K. I. Beynon et al., Pestic. Sci. 3, 689 (1972). Neurophysiological action: R. B. Morton, D. R. Gardner, Experientia 32, 611 (1976).

Chemical structure

Properties

Crystalline solid, mp 174-176°, resolidifies and melts again at 185-187°. Vapor pressure at 20°: 1.4 × 107 mm Hg. Soly in water at 20°: 0.02 mg/l. Soly at 20° (g/l): carbon tetrachloride 300; chloroform 450; tetrachloroethylene 255. Stable to heat and alkali but hydrolyzed by mild acidic conditions. LD50 orally in rats: 1200-2000 mg/kg (Boyce).

Use

As molluscicide (against snails carrying bilharzia flukes).

Status

This monograph has been retired and is no longer subject to revision or update.