13-09840. Trolnitrate Phosphate [Archived]

Nomenclature

CAS number: 588-42-1
2,2′2′′-Nitrilotrisethanol trinitrate (ester) phosphate (1:2) (salt); triethanolamine trinitrate biphosphate; trinitrotriethanolamine diphosphate; tri(2-nitroxyethyl)amine biphosphate; tris(2-nitroxyethyl)amine biphosphate; Bentonyl (Bengue); Duronitrin (Andrews); Metamine (Pfizer); Nitretamin (BMS); Nitroduran (Leo Pharm); Ortin (Wild); Praenitron (Pfizer); Vasomed (Medo-Chem.).
C6H18N4O17P2; mol wt 480.17.
C 15.01%, H 3.78%, N 11.67%, O 56.64%, P 12.90%.

Description and references

Coronary vasodilator. Prepd by the nitration of triethanolamine followed by precipitation with phosphoric acid: Metadiet, FR 984523 (1951); Junkmann et al., DE 830955 (1952 to Schering).

Chemical structure

Properties

Crystals, mp 107-109°.

Therapeutic Category

Antianginal.

Keywords

Antianginal; Vasodilator (Coronary)

Status

This monograph has been retired and is no longer subject to revision or update.