Cineole

1,8-Cineole, Eucalyptol, 1,8-epoxy-p-menthane; C₁₀H₁₈O = 154.3 (470-82-6)

Colourless liquid, practically insoluble in water, miscible with anhydrous ethanol.

, 0.922 to 0.927; , 1.465 to 1.459.

Freezing point (2.2.18): 0° to 1°.

Distillation range (2.2.11): 174° to 177°.

Phenol Shake 1 g with 20 mL of water. Allow to separate and add to 10 mL of the aqueous layer 0.1 mL of ferric chloride solution R1. No violet colour develops.

Turpentine oil Dissolve 1 g in 5 mL of ethanol (90% v/v). Add dropwise freshly prepared bromine water. Not more than 0.5 mL is required to give a yellow colour lasting for 30 minutes.

Residue on evaporation: maximum 0.05%.

To 10.0 mL add 25 mL of water, evaporate on a water-bath and dry the residue to constant mass at 100-105°.

Cineole used in gas chromatography complies with the following additional test.

Assay Gas chromatography (2.2.28) as prescribed in the monograph Peppermint oil (0405).

Test solution The substance to be examined.

Content, minimum 98.0%, calculated by the normalisation procedure.