Oxymetholone Tablets

note: Oxymetholone Tablets are not currently licensed in the United Kingdom.

Action and use

Anabolic steroid; androgen.

Definition

Oxymetholone Tablets contain Oxymetholone.

The tablets comply with the requirements stated under Tablets, the requirements stated under Unlicensed Medicines and with the following requirements.

Content of oxymetholone, C₂₁H₃₂O₃

90.0 to 110.0% of the stated amount.

Identification

To a quantity of the powdered tablets containing 50 mg of Oxymetholone add 10 mL of water, extract with two 10 mL quantities of chloroform and evaporate the chloroform extract to dryness. The residue, after drying over phosphorus pentoxide at a pressure not exceeding 0.7 kPa, complies with the following tests.

A. The infrared absorption spectrum, Appendix II A, is concordant with the reference spectrum of oxymetholone (RS 256).

B. Complies with the test for identification of steroids, Appendix III A, using impregnating solvent II and mobile phase D.

Assay

Weigh and powder 20 tablets. Extract a quantity of the powder containing 25 mg of Oxymetholone with 0.01m ethanolic sodium hydroxide and add sufficient 0.01m ethanolic sodium hydroxide to produce 250 mL. Filter if necessary, dilute 5 mL of the filtrate to 50 mL with 0.01m ethanolic sodium hydroxide and measure the absorbance of the resulting solution at the maximum at 315 nm, Appendix II B. Calculate the content of C₂₁H₃₂O₃ taking 547 as the value of A(1%, 1 cm) at the maximum at 315 nm.

Storage

Oxymetholone Tablets should be kept free from contact with ferrous metals and protected from light.