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Page 295



		11 Clinical Pharmacology in Drug Development: A View to Future Effectiveness



		J. Robert Powell, Alan Bye, and Paul D. Rubin Glaxo-Wellcome Inc. Research Triangle Park, North Carolina



		I. Introduction



		296



		II. Current Environment



		297



		III. The Challenge



		298



		IV. Core Competencies



		298



		V. Applications of Science To Drug Development



		299



		VI. Current and Future Needs



		308



		VII. Management/Organization



		308



		VIII. Science



		312



		IX. People



		312



		X. Conclusion



		313



		References



		314

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