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Fig. 4
Bottom fit curves remifentanil arterial blood concentration versus EEG
spectral edge in a healthy volunteer given a 20-minute infusion. The upper left
curve shows the hysteresis and the right curve shows the collapsed curve
after fitting. |
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the analytical measures were varied, a new study was conducted in 18 adults given 3 alcohol doses (0.15, 0.3, and 0.6 g/kg). The same experimental conditions were employed with and without ranitidine, but with a sensitive, specific ethanol assay covering the concentration range [11]. This study found that while no interaction could be determined at the two higher doses (contradicting |
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