Mebendazole

A to Z Drug Facts

Mebendazole

  Action
  Indications
  Contraindications
  Route/Dosage
  Interactions
  Lab Test Interferences
  Adverse Reactions
  Precautions
Patient Care Considerations
  Administration/Storage
  Assessment/Interventions
  Patient/Family Education


(meh-BEND-uh-zole)
Vermox
Class: Antihelmintic

 Action Kills parasitic worms by blocking glucose uptake, thus depleting stored glycogen. Without glycogen, parasite cannot reproduce or survive.

 Indications Treatment of pinworm (Enterobius vermicularis), round worm (Ascaris lumbricoides), common hookworm (Ancylostoma duodenale), American hookworm (Necator americanus) and whipworm (Trichuris trichiura) in single or mixed parasitic infections.

 Contraindications Standard considerations.

 Route/Dosage

Trichuriasis, Ascariasis and Hookworm Infection

ADULTS & CHILDREN: PO 100 mg tablet AM and PM on 3 consecutive days.

Ascaris Infection

ADULTS & CHILDREN: Alternative dose: PO 500 mg as single dose.

Enterobiasis

ADULTS & CHILDREN: PO 100 mg as single dose.

 Interactions

Carbamazepine; hydantoins (eg, phenytoin): Pharmacological effects of mebendazole may be decreased.

 Lab Test Interferences None well documented.

 Adverse Reactions

GI: Transient abdominal pain and diarrhea. OTHER: Fever.

 Precautions

Pregnancy: Category C. Lactation: Undetermined. Children: Safety and efficacy in children < 2 yr not established.


PATIENT CARE CONSIDERATIONS


 Administration/Storage

 Assessment/Interventions

OVERDOSAGE: SIGNS & SYMPTOMS
  GI complaints

 Patient/Family Education

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Copyright
© 2003 Facts and Comparisons
David S. Tatro
A to Z Drug Facts