Telmisartan

A to Z Drug Facts

Telmisartan

  Action
  Indications
  Contraindications
  Route/Dosage
  Interactions
  Lab Test Interferences
  Adverse Reactions
  Precautions
Patient Care Considerations
  Administration/Storage
  Assessment/Interventions
  Patient/Family Education


(tell-mih-SAHR-tan)
Micardis
Tablets: 40 mg
Tablets: 80 mg
Class: Antihypertensive, Angiotensin II antagonist

  Action Antagonizes the effect of angiotensin II (vasoconstriction and aldosterone secretion) by blocking the angiotensin II (AT1 receptor) in vascular smooth muscle and the adrenal gland, producing decreased BP.

  Indications Treatment of hypertension.

  Contraindications Standard considerations.

  Route/Dosage

Adults: PO 20 to 80 mg/day; usual starting dose 40 mg/day.

  Interactions

Digoxin: May increase plasma levels of digoxin, that may increase toxicity.

Lithium: Plasma concentrations may be increased by telmisartan, resulting in an increase in the pharmacologic and adverse effects of lithium.

  Lab Test Interferences None well documented.

  Adverse Reactions

EENT: Sinusitis; pharyngitis. GI: Diarrhea. RESPIRATORY: Upper respiratory tract infection. OTHER: Back pain.

  Precautions

Pregnancy: Category C (first trimester); category D (second and third trimester). Can cause injury or death to the fetus if used during second or third trimester. Lactation: Undetermined. CHILDREN: Safety and efficacy not established. Renal function impairment: Use with caution in patients whose renal function may depend on the activity of the renin-angiotensin-aldosterone system (eg, patients with severe CHF); use may be associated with oliguria, progressive azotemia, acute renal failure, and death. Hepatic function impairment: Use with caution.


PATIENT CARE CONSIDERATIONS


  Administration/Storage

  Assessment/Interventions

OVERDOSAGE: SIGNS & SYMPTOMS
 Hypotension, dizziness, tachycardia, bradycardia

  Patient/Family Education

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© 2003 Facts and Comparisons
David S. Tatro
A to Z Drug Facts