Nomenclature
CAS number: 76-24-4
5,5′-Dihydroxy-[5,5′-bipyrimidine]-2,2′,4,4′,6,6′(1
H,1′
H,3
H,3′
H,5
H,5′
H)-hexone; 5,5′-dihydroxy-5,5′-bibarbituric acid; uroxin.
C
8H
6N
4O
8; mol wt 286.16.
C 33.58%, H 2.11%, N 19.58%, O 44.73%.
Description and references
Prepd from uric acid: Nightingale, Org. Synth. coll. vol. III, 42
(1955); from alloxan monohydrate: Tipson, ibid. coll.
vol. IV, 25 (1963). Structure: Singh, Acta Crystallogr. 19, 767 (1965).
Derivative
Dihydrate.
Properties
Cryst powder. On exposure to air becomes red.
Becomes yellow at 225°; dec at 253-255°. Sparingly sol in cold water,
alcohol or ether. Its aq soln is acid; reduces Ag salts and gives
a blue ppt with Ba(OH)2 soln. Keep
tightly closed. Emits toxic fumes upon decompn.Caution
Ingestion causes disturbed carbohydrate
metabolism leading to diabetes, cf. Dangerous Properties
of Industrial Materials, N. I. Sax, Ed. (Van Nostrand Reinhold,
New York, 4th ed., 1975) p 366.