468. 2-Aminopropanol

Nomenclature

CAS number: 78-91-1
2-Amino-1-propanol; 2-aminopropyl alcohol; β-propanolamine; 2-hydroxyisopropylamine.
C3H9NO; mol wt 75.11.
C 47.97%, H 12.08%, N 18.65%, O 21.30%.

Description and references

Obtained together with isopropylamine on reduction of acetylcarbinoloxime with sodium amalgam in dilute acetic acid: Gabriel, Ber. 49, 2121 (1916); from dl-alanylglycine by reduction with sodium and abs alcohol: Abderhalden, Schwab, Z. Physiol. Chem. 143, 292 (1925); by boiling the ethyl ester of dl-acetylalanine with sodium in abs alcohol: Karrer, Helv. Chim. Acta 4, 98 (1921); as hydrolytic cleavage product of ergonovine and ergometrinine: Stoll, Hofmann, ibid. 26, 956 (1943); by catalytic hydrogenation of the ethyl ester of alanine: Adkins, Pavlic, J. Am. Chem. Soc. 69, 3039 (1947).

Chemical structure

Derivative

dl-Form.

Properties

Liquid, fishy odor. bp 173-176°. Freely sol in water, alcohol, ether.

Derivative

Hydrochloride.
C3H9NO.HCl; mol wt 111.57.
C 32.30%, H 9.03%, N 12.55%, O 14.34%, Cl 31.78%.

Properties

Leaflets from abs alcohol + acetone, dec 86-87.5°.