954. Bamethan

Nomenclature

CAS number: 3703-79-5
α-[(Butylamino)methyl]-4-hydroxybenzenemethanol; α-[(butylamino)methyl]-p-hydroxybenzyl alcohol; 1-(p-hydroxyphenyl)-2-butylaminoethanol; 1-(4-hydroxyphenyl)-1-hydroxy-2-butylaminoethane; 2-butylamino-1-p-hydroxyphenylethanol.
C12H19NO2; mol wt 209.28.
C 68.87%, H 9.15%, N 6.69%, O 15.29%.

Description and references

Prepn: Corrigan et al., J. Am. Chem. Soc. 67, 1894 (1945); Kovács, Pharm. Zentralhalle 92, 193 (1953), C.A. 49, 936 (1955). Metabolism of sulfate: Hajos, Szporny, Arzneim.-Forsch. 18, 1212 (1968).

Chemical structure

Properties

Crystals, mp 123.5-125°.

Derivative

Hydrochloride.
C12H19NO2.HCl; mol wt 245.75.
C 58.65%, H 8.20%, N 5.70%, O 13.02%, Cl 14.43%.

Properties

mp 109-110°.

Derivative

Sulfate.

Nomenclature

CAS number: 5716-20-1
Vasculat (Boehringer, Ing.); Vasculit (Boehringer, Ing.); Bupatol (Gedeon Richter); Garmian (Fuso).
(C12H19NO2)2.H2SO4; mol wt 516.65.
C 55.79%, H 7.80%, N 5.42%, O 24.77%, S 6.21%.

Therapeutic Category

Vasodilator (peripheral).

Keywords

Vasodilator (Peripheral)