1177. Bestmann-Ohira Reagent
Nomenclature
CAS number: 90965-06-3
(1-Diazo-2-oxopropyl)phosphonic acid dimethyl ester; dimethyl (1-diazo-2-oxopropyl)phosphonate. C5H9N2O4P; mol wt 192.11.
C 31.26%, H 4.72%, N 14.58%, O 33.31%, P 16.12%.
Description and references
Diazoalkylphosphonate reagent; converted in situ to the Seyferth-Gilbert reagent, q.v. Prepn: P. Callant et al., Synth. Commun. 14, 155 (1984). Synthetic applications: S. Ohira, ibid. 19, 561 (1989); S. Müller et al., Synlett 1996, 521; G. J. Roth et al., Synthesis 2004, 59; E. Quesada, R. J. K. Taylor, Tetrahedron Lett. 46, 6473 (2005).
