1506. Butabarbital Sodium
Nomenclature
CAS number: 143-81-7
5-Ethyl-5-(1-methylpropyl)-2,4,6(1H,3H,5H)-pyrimidinetrione sodium salt; 5-sec-butyl-5-ethylbarbituric acid sodium salt; 5-ethyl-5-(1-methylpropyl)barbituric acid sodium salt; sodium 5-sec-butyl-5-ethylbarbiturate; sodium 5-ethyl-5-(1-methylpropyl)barbiturate; secbutobarbitone sodium; Asturidon (Cilag); Bubarbital Sodium (Philips Roxane); Butabarbitone Sodium; Busodium (Truxton); Busotran (Galen); Butabon; Butabar (Flar); Butak (Lemmon); Buta-Kay (King); Butrate (Kay); Butte (Scrip); Buticaps (McNeil); Butalan (Lannett); Butanotic (Medical Arts); Butex (Phillips); Butatran (Palmedico); Butazem (Zemmer); Carrbutabarb (Century); Butased (Schlicksup); Butisol Sodium (McNeil); Loubarb; Neravan (Promonta); Prelital; Sarisol (Halsey). C10H15N2NaO3; mol wt 234.23.
C 51.28%, H 6.45%, N 11.96%, Na 9.82%, O 20.49%.
Description and references
Prepn: Shonle, US 1856792 (1932 to Lilly).
Properties
Bitter powder. (The free acid mp 165-168°.) One gram dissolves in 2 ml water, in about 7 ml alcohol. Practically insol in ether, benzene. The pH of 10% aq soln 10.0-11.2 (USP XXI, 1985).Note
This is a controlled substance (depressant): 21 CFR, 1308.13.Therapeutic Category
Sedative, hypnotic.
Keywords
Sedative/Hypnotic; Barbituric Acid Derivatives