1516. Butaperazine

Nomenclature

CAS number: 653-03-2
1-[10-[3-(4-Methyl-1-piperazinyl)propyl]-10H-phenothiazin-2-yl]-1-butanone; 2-butyryl-10-[3-(4-methyl-1-piperazinyl)propyl]phenothiazine; N-[γ-(4′-methyl-1′-piperazinyl)propyl]-3-butyrylphenothiazine; butyrylperazine; Bayer 1362; Repoise (Robins); Tyrylen.
C24H31N3OS; mol wt 409.59.
C 70.38%, H 7.63%, N 10.26%, O 3.91%, S 7.83%.

Description and references

Prepn: Hoerlein et al., DE 1120451 (1961 to Bayer), C.A. 57, 4677c (1962).

Chemical structure

Properties

bp0.05 270-280°.

Derivative

Dimaleate.

Nomenclature

CAS number: 1063-55-4
Randolectil (Bayer).
C24H31N3OS.2C4H4O4; mol wt 641.73.
C 59.89%, H 6.13%, N 6.55%, O 22.44%, S 5.00%.

Derivative

Maleate.
C24H31N3OS.C4H4O4; mol wt 525.66.
C 63.98%, H 6.71%, N 7.99%, O 15.22%, S 6.10%.

Properties

Crystals from carbon tetrachloride, mp 180-182°.

Therapeutic Category

Antipsychotic.

Keywords

Antipsychotic; Phenothiazines