1521. Butethal
Nomenclature
CAS number: 77-28-1
5-Butyl-5-ethyl-2,4,6(1H,3H,5H)-pyrimidinetrione; 5-butyl-5-ethylbarbituric acid; butobarbitone; Soneryl (M & B); Neonal (Abbott); Butobarbital; Etoval. C10H16N2O3; mol wt 212.25.
C 56.59%, H 7.60%, N 13.20%, O 22.61%.
Description and references
Prepn: US 1609520 (1926). Pharmacology and toxicity: G. A. Alles et al., J. Pharmacol. Exp. Ther. 89, 356 (1947).
Properties
Crystals. Slightly bitter taste. mp 124-127°. One gram dissolves in about 5 ml alcohol, 10 ml ether. Practically insol in water; insol in petr ether, aliphatic hydrocarbons. LD50 i.p. in mice: 1.506 mM/kg (Alles).Note
This is a controlled substance (depressant): 21 CFR, 1308.13.Therapeutic Category
Sedative, hypnotic.
Keywords
Sedative/Hypnotic; Barbituric Acid Derivatives