1522. Butethamate

Nomenclature

CAS number: 14007-64-8
Benzeneacetic acid α-ethyl-2-(diethylamino)ethyl ester; 2-phenylbutyric acid 2-(diethylamino)ethyl ester; β-diethylaminoethyl ethylphenylacetate; 2-diethylaminoethyl 2-phenylbutyrate.
C16H25NO2; mol wt 263.38.
C 72.96%, H 9.57%, N 5.32%, O 12.15%.

Description and references

Prepn: Di Paco, Tauro, Farmaco Ed. Sci. 11, 540 (1956); CH 291375 (1953 to AG Hommel's Haematogen) and CH 292596 (1953 to Chem. Fabrik “PARA”), C.A. 49, 2505a,c (1955). Pharmacology: Jordan, Arzneim.-Forsch. 8, 716 (1958); Fleisch et al., ibid. 11, 1119 (1961).

Chemical structure

Properties

bp11 167-169°. nD20 1.4909.

Derivative

Citrate.

Nomenclature

CAS number: 3639-12-1
Abuphenine; Convenil (Hommel); Hicoseen (Klimitschek); Phenesin; Phenetin (Alpinapharm).
C16H25NO2.C6H8O7; mol wt 455.50.
C 58.01%, H 7.30%, N 3.08%, O 31.61%.

Properties

Crystals from abs alcohol, mp 109-110°. Freely sol in water, alcohol.

Therapeutic Category

Antitussive.

Keywords

Antitussive