2107. Chlormidazole

Nomenclature

CAS number: 3689-76-7
1-[(4-Chlorophenyl)methyl]-2-methyl-1H-benzimidazole; 1-(p-chlorobenzyl)-2-methylbenzimidazole; 2-methyl-1-(p-chlorobenzyl)benzimidazole; clomidazole.
C15H13ClN2; mol wt 256.73.
C 70.18%, H 5.10%, Cl 13.81%, N 10.91%.

Description and references

Prepn: Herrling et al., US 2876233 (1959 to Grünenthal).

Chemical structure

Properties

bp12 240-242°.

Derivative

Monohydrate.

Properties

mp 67-68°.

Derivative

Hydrochloride.

Nomenclature

CAS number: 74298-63-8
H-115; Diamyceline (Diamant); Futrican (Astra).
C15H13ClN2.HCl; mol wt 293.19.
C 61.45%, H 4.81%, Cl 24.18%, N 9.55%.

Properties

mp 227-228°.

Therapeutic Category

Antifungal.

Keywords

Antifungal (Synthetic); Imidazoles