2397. Clopidol

Nomenclature

CAS number: 2971-90-6
3,5-Dichloro-2,6-dimethyl-4-pyridinol; meticlorpindol; clopindol; Coyden (Dow).
C7H7Cl2NO; mol wt 192.04.
C 43.78%, H 3.67%, Cl 36.92%, N 7.29%, O 8.33%.

Description and references

Prepn: Stevenson, US 3206358 (1965 to Dow). Metabolism studies in chickens: Smith, Poult. Sci. 48, 420 (1969). Toxicity study: Plisek et al., Vet. Spofa 12, 111 (1970), C.A. 74, 138780p (1971).

Chemical structure

Properties

Solid, mp >320°. Practically insol in water. LD50 orally in rats: 18 g/kg (Plisek).

Caution

Potential symptoms of overexposure are irritation of eyes, skin, nose, throat; cough. See NIOSH Pocket Guide to Chemical Hazards (DHHS/NIOSH 97-140, 1997) p 72.

Therapeutic Category (Veterinary)

Coccidiostat.