2719. Cyclodrine

Nomenclature

CAS number: 52109-93-0
1-Hydroxy-α-phenylcyclopentaneacetic acid 2-diethylaminoethyl ester; β-diethylaminoethyl (1-hydroxycyclopentyl)phenylacetate; 2-phenyl-2-(1-hydroxycyclopentyl)acetic acid β-(diethylamino)ethyl ester.
C19H29NO3; mol wt 319.44.
C 71.44%, H 9.15%, N 4.38%, O 15.03%.

Description and references

Anticholinergic. Prepn: Blicke, US 2922795 (1960 to Univ. of Michigan). Activity studies: Lands, Luduena, J. Pharmacol. Exp. Ther. 117, 331 (1956); Karczman, Long, ibid. 123, 230 (1958).

Chemical structure

Derivative

Hydrochloride.

Nomenclature

CAS number: 78853-39-1
GT-92; Cyclopent (Jenapharm).
C19H29NO3.HCl; mol wt 355.90.
C 64.12%, H 8.50%, N 3.94%, O 13.49%, Cl 9.96%.

Properties

Crystals from isopropanol-isopropyl ether, mp 133-135°.

Therapeutic Category

Mydriatic.

Keywords

Antimuscarinic; Mydriatic