2847. Decamethonium Bromide

Nomenclature

CAS number: 541-22-0
N1,N1,N1,N10,N10,N10-Hexamethyl-1,10-decanediaminium bromide (1:2); N,N,N,N′,N′,N′-Hexamethyl-1,10-decanediaminium dibromide; decamethylenebis[trimethylammonium bromide]; C-10; Syncurine (Burroughs Wellcome).
C16H38Br2N2; mol wt 418.29.
C 45.94%, H 9.16%, Br 38.21%, N 6.70%.

Description and references

Prepn: Blomquist et al., J. Am. Chem. Soc. 81, 678 (1959).

Chemical structure

Properties

Crystals from methanol + acetone, dec 268-270°. Freely sol in water, alcohol; very slightly sol in chloroform. Practically insol in ether. Aq solns are stable and may be sterilized by autoclaving.

Therapeutic Category

Neuromuscular blocking agent.

Keywords

Neuromuscular Blocking Agent; Depolarizing Agents