2897. Deoxo-Fluor(R) (Air Prods. Chem.)

Nomenclature

CAS number: 202289-38-1
(T-4)-Trifluoro[2-methoxy-N-(2-methoxyethyl)ethanaminato-κN]sulfur; bis(2-methoxyethyl)aminosulfur trifluoride.
C6H14F3NO2S; mol wt 221.24.
C 32.57%, H 6.38%, F 25.76%, N 6.33%, O 14.46%, S 14.49%.

Description and references

Broad-spectrum deoxofluorinating agent. Prepn: G. S. Lal et al., EP 908448; eidem US 6207860 (1999, 2001 both to Air Prods. Chem.); idem et al., Chem. Commun. 1999, 215; idem et al., J. Org. Chem. 64, 7048 (1999). Review of use in fluorination reactions of organic compds: R. P. Singh, J. M. Shreeve, Synthesis 2002, 2561-2578.

Chemical structure

Properties

Yellow liquid, colorless after distillation. bp10 60°. Dec onset ≈140°. d 1.2. Sol in hexane, ethers, halogenated organics, toluene.

Caution

Reacts violently with water to form HF.

Use

Versatile, thermally stable nucleophilic fluorinating reagent.