Nomenclature
CAS number: 6807-82-5
N-[
N-[4-[[(2-Amino-1,4-dihydro-4-oxo-6-pteridinyl)methyl]amino]benzoyl]-
l-α-glutamyl]-
l-glutamic acid; pteroyl-α-glutamylglutamic acid; pteroyldiglutamic acid; PDGA.
C
24H
26N
8O
9; mol wt 570.51.
C 50.53%, H 4.59%, N 19.64%, O 25.24%.
Description and references
Folic acid analog. Synthesis: Mowat et al., J. Am. Chem. Soc. 70, 1096 (1948); Hutchings, and Geraci, US 2500825 and US 2501168 (both 1950 to Am. Cyanamid); Geraci, US 2766240 (1956 to Aries Labs.).