3490. Ecamsule

Nomenclature

CAS number: 92761-26-7
3,3′-(1,4-Phenylenedimethylidyne)bis[7,7-dimethyl-2-oxo-bicyclo[2.2.1]heptane-1-methanesulfonic acid]; terephthalylidene-3,3′-dicamphor-10,10′-disulfonic acid; Mexoryl SX (L'Oreal).
C28H34O8S2; mol wt 562.69.
C 59.77%, H 6.09%, O 22.75%, S 11.40%.

Description and references

Broad spectrum UVA absorber with some UVB absorption. Prepn: G. Lang et al., DE 3321679; eidem, US 4585597 (1983, 1986 both to L'Oreal). Evaluation of photomutagenicity: S.W. Dean et al., Mutagenesis 7, 179 (1992). Evaluation of photoprotection: A. Fourtanier et al., Photochem. Photobiol. 55, 549 (1992); R. D. Ley, A. Fourtanier, ibid. 65, 1007 (1997).

Chemical structure

Properties

Solid, mp 255° (dec). uv max (ethanol): 345 nm (ε 47000 M-1cm-1); uv max (water): 342 nm (ε 42300).

Therapeutic Category

Ultraviolet screen.

Keywords

Ultraviolet Screen