3871. Etiproston

Nomenclature

CAS number: 59619-81-7
(5Z)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(1E)-2-[2-(phenoxymethyl)-1,3-dioxolan-2-yl]ethenyl]cyclopentyl]-5-heptenoic acid; (5Z,13E)-(8R,9S,11R,12R)-9,11-dihydroxy-15,15-ethylenedioxy-16-phenoxy-17,18,19,20-tetranorprostadienoic acid; 15-deoxy-15,15-ethylenedioxy-16-phenoxy-17,18,19,20-tetranorprostaglandin F; Prostavet (Virbac); Vetiprost (Virbac).
C24H32O7; mol wt 432.51.
C 66.65%, H 7.46%, O 25.89%.

Description and references

Prostaglandin F analog with estrus cycle synchronizing activity. Prepn: W. Skuballa et al., DE 2434133; eidem, US 4088775 (1976, 1978 both to Schering AG); and biological activity: W. Skuballa et al., J. Med. Chem. 21, 443 (1978).

Chemical structure

Properties

Colorless oil.

Therapeutic Category (Veterinary)

Luteolytic.