4166. Fluoroacetamide

Nomenclature

CAS number: 640-19-7
Fluoroacetic acid amide; monofluoroacetamide; 1081; Fluorakil 100; Fussol (Sankyo).
C2H4FNO; mol wt 77.06.
C 31.17%, H 5.23%, F 24.65%, N 18.18%, O 20.76%.
CH2FCONH2.

Description and references

Numerous syntheses, e.g. from fluoroacetyl chloride and NH3: Truce, J. Am. Chem. Soc. 70, 2828 (1948). Mode of action study and toxicity data: F. Matsumura, R. D. O'Brien, Biochem. Pharmacol. 12, 1201 (1963).

Properties

Crystals. Sublimes on heating. Freely sol in water; sol in acetone; sparingly sol in chloroform. LD50 i.p. in mice: 85 mg/kg (Matsumura, O'Brien).

Use

Rodenticide. Insecticide proposed mainly for use on fruits to combat scale insects, aphids, and mites.