Description and references

Amino sugar isolated from chondroitin sulfate, q.v.: P. A. Levene, F. B. La Forge, J. Biol. Chem. 18, 123 (1914). Sepn of α- and β-anomers: P. A. Levene, ibid. 57, 337 (1923). Synthesis: S. P. James et al., Nature 156, 308 (1945) eidem, J. Chem. Soc. 1946, 625; R. Kuhn, W. Kirschenlohr, Ann. 600, 126 (1956); P. A. Gent et al., J. Chem. Soc. Perkin Trans. 1 1972, 277. Chemistry: D. Horton in The Amino Sugars Vol. 1A, R. W. Jeanloz, Ed. (Academic, New York, 1969) pp 133-145. Inducer of exptl hepatitis: D. Keppler et al., Exp. Mol. Pathol. 9, 279 (1968); K. Decker, D. Keppler in Progress in Liver Diseases Vol. IV, H. Popper, F. Schaffner, Eds. (Grune & Stratton, New York, 1972) p 183. Powerful inhibitor of hepatic RNA synthesis: D. Keppler et al., J. Biol. Chem. 249, 211 (1974); T. Anukarahanonta et al., Eur. J. Cancer 16, 1171 (1980).

Derivative