5467. Levophacetoperane

Nomenclature

CAS number: 24558-01-8
α-Phenyl-2-piperidinemethanol acetate; threo-1-acetoxy-1-phenyl-1-(2-piperidyl)methane; acetic acid α-phenyl-2-piperidylmethyl ester; 1-phenyl-1-(2′-piperidyl)-1-acetoxymethane; phacetoperane; RP-8228.
C14H19NO2; mol wt 233.31.
C 72.07%, H 8.21%, N 6.00%, O 13.72%.

Description and references

Prepn: Jacob, Joseph, US 2928835 (1960 to Rhne-Poulenc).

Chemical structure

Derivative

Hydrochloride.

Nomenclature

CAS number: 23257-56-9
Lidepran.
C14H19NO2.HCl; mol wt 269.77.
C 62.33%, H 7.47%, N 5.19%, O 11.86%, Cl 13.14%.

Properties

Crystals from acetone + ether, mp 229-230°. Levorotatory.

Therapeutic Category

Antidepressant; anorexic.

Keywords

Anorexic; Antidepressant