5854. Mephobarbital

Nomenclature

CAS number: 115-38-8
5-Ethyl-1-methyl-5-phenyl-2,4,6(1H,3H,5H)-pyrimidinetrione; 5-ethyl-1-methyl-5-phenylbarbituric acid; 5-phenyl-5-ethyl-3-methylbarbituric acid; N-methylethylphenylbarbituric acid; methylphenobarbital; Phemiton (Pliva); Prominal; Mebaral (Winthrop).
C13H14N2O3; mol wt 246.26.
C 63.40%, H 5.73%, N 11.38%, O 19.49%.

Description and references

Prepn: Taub, Kropp, DE 537366 (1929 to I. G. Farben.).

Chemical structure

Properties

White, tasteless crystals. mp 176°. Slightly sol in cold, freely in hot water or in alcohol.

Note

This is a controlled substance (depressant): 21 CFR, 1308.14.

Therapeutic Category

Anticonvulsant; sedative; hypnotic.

Therapeutic Category (Veterinary)

Anticonvulsant; sedative; hypnotic.

Keywords

Anticonvulsant; Sedative/Hypnotic; Barbituric Acid Derivatives