5902. MES
Nomenclature
CAS number: 4432-31-9
4-Morpholineethanesulfonic acid; 2-(4-morpholino)ethyl sulfonate; 2-(N-morpholino)ethanesulfonic acid. C6H13NO4S; mol wt 195.24.
C 36.91%, H 6.71%, N 7.17%, O 32.78%, S 16.42%.
Description and references
One of the zwitterionic N-substituted aminosulfonic acids known as Good Buffers, active in the pH range 6-8. Prepn as sodium salt: S. Malkiel, J. P. Mason, J. Org. Chem. 8, 199 (1943); as acid: N. E. Good et al., Biochemistry 5, 467 (1966). Thermodynamic parameters: C. D. McGlothlin, J. Jordan, Anal. Lett. 9, 245 (1976). Acid-base properties: A. Balikungeri, Chimia 43, 13 (1989). Interference with protein determn: P. L. Lleu, G. Rebel, Anal. Biochem. 192, 215 (1991). Use as buffer: S. C. Lee et al., J. AOAC Int. 75, 395 (1992); P. J. Henney et al., Anim. Genet. 25, 363 (1994).
