5947. Methamidophos

Nomenclature

CAS number: 10265-92-6
Phosphoramidothioic acid O,S-dimethyl ester; O,S-dimethyl phosphoramidothioate; Bayer 71628; ENT-27396; Ortho 9006; SRA-5172; Monitor (Bayer CropSci.); Tamaron (Bayer CropSci.).
C2H8NO2PS; mol wt 141.13.
C 17.02%, H 5.71%, N 9.92%, O 22.67%, P 21.95%, S 22.72%.

Description and references

Prepn: W. Lorenz et al., BE 666143 (1965 to Bayer), C.A. 65, 16864f (1966); NL 6602588; P. S. Magee, US 3309266 (both 1967 to Chevron). Activity: I. Hammann, Pflanzenschutz-Nachr. 23, 140 (1970). Acute toxicity: T. B. Gaines, R. E. Linder, Fundam. Appl. Toxicol. 7, 299 (1986). Review of properties and metabolism: A. M. A. Khasawinah et al., Pestic. Biochem. Physiol. 9, 211-221 (1978).

Chemical structure

Properties

Crystals from ether, mp 54°. nD40 1.5092; d44.5 1.31. Vapor pressure at 30°: 3 × 104 mm Hg. Readily sol in water, ethanol. LD50 in adult male, female rats (mg/kg): 25, 27 orally (Gaines, Linder).

Use

Insecticide; acaricide.