6116. Methyl Pyridyl Ketone

Nomenclature

CAS number: 350-03-8
1-(3-Pyridinyl)ethanone; 3-acetylpyridine; β-acetylpyridine; methyl 3-pyridyl ketone; methyl β-pyridyl ketone.
C7H7NO; mol wt 121.14.
C 69.40%, H 5.82%, N 11.56%, O 13.21%.

Description and references

A nicotinic acid antagonist. Prepd in dry distillation of Ca-nicotinate with Ca-acetate. The ketone is isolated through the phenylhydrazone: Engler, Kiby, Ber. 22, 597 (1889).

Chemical structure

Properties

Liquid, bp 220°. Freely sol in acids.

Derivative

Ketoxime.
NC5H4C(CH3)=NOH.

Properties

Crystals from alcohol or benzene, mp 112°.

Derivative

Ketoxime hydrochloride.

Properties

Crystals from alcohol, mp 204°.

Derivative

Phenylhydrazone.
NC5H4C(CH3)=NNHC6H5.

Properties

Yellow needles from alcohol, mp 137°.