8331. Salicylhydroxamic Acid

Nomenclature

CAS number: 89-73-6
N,2-Dihydroxybenzamide; 2-hydroxybenzhydroxamic acid; 2-hydroxyphenylhydroxamic acid.
C7H7NO3; mol wt 153.14.
C 54.90%, H 4.61%, N 9.15%, O 31.34%.

Description and references

Prepn: Jeanrenaud, Ber. 22, 1272 (1889); Urbanski, Nature 166, 267 (1950). Trypanocidal activity: F. Opperdoes et al., Exp. Parasitol. 40, 198 (1976); A. B. Clarkson, F. H. Brohn, Science 194, 204 (1976); A. J. Barnicoat et al., Experientia 37, 1291 (1981).

Chemical structure

Properties

Needles from acetic acid, mp 168° (slow heating), mp 176-178° (quick heating). Sublimes. pK (25°) 4.19.

Derivative

Sodium salt.

Nomenclature

CAS number: 2460-25-5
C7H6NNaO3; mol wt 175.12.
C 48.01%, H 3.45%, N 8.00%, Na 13.13%, O 27.41%.

Properties

Plates. Freely sol in water. pH of 0.1N soln 7.7.

Use

Complexing agent.