9214. Tetrahydrogestrinone

Nomenclature

CAS number: 618903-56-3
(17α)-13-Ethyl-17-hydroxy-18,19-dinorpregna-4,9,11-trien-3-one; 18a-homo-pregna-4,9,11-trien-17β-ol-3-one; THG.
C21H28O2; mol wt 312.45.
C 80.72%, H 9.03%, O 10.24%.

Description and references

Androgen and progestin; hydrogenation product of gestrinone, q.v. Discovery, synthesis, LC/MS/MS and GC/MS determn in urine: D. H. Catlin et al., Rapid Commun. Mass Spectrom. 18, 1245 (2004). Hormonal properties: A. K. Death et al., J. Clin. Endocrinol. Metab. 89, 2498 (2004). In vitro metabolism study: J.-F. Lévesque et al., Anal. Chem. 77, 3164 (2005).

Chemical structure

Properties

Absorption max: 345 nm.

Note

This is a controlled substance (anabolic steroid): 21 CFR, 1308.13, as defined in 1300.01.