10015. Vitamin B12, Radioactive

Nomenclature

Radioactive cyanocobalamin; radiocyanocobalamin.

Description and references

Prepn of 60Co labelled compound: Chaiet et al., Science 111, 601 (1950). Properties identical with unlabelled vitamin B12, except for the presence of radioactive cobalt. Evaluation of dual-isotope Schilling test for pernicious anemia: L. S. Zuckier, L. R. Chervu, J. Nucl. Med. 25, 1032 (1984).

Derivative

60Co Vitamin B12.

Nomenclature

CAS number: 13422-53-2
Racobalamin-60 (Abbott); Rubratope-60 (BMS).

Properties

T 5.27 years, emitting beta and gamma rays.

Derivative

58Co Vitamin B12.

Nomenclature

CAS number: 18195-32-9

Properties

T 70.8 days, emitting beta, gamma and x-rays.

Derivative

57Co Vitamin B12.

Nomenclature

CAS number: 13115-03-2
Rubratope-57 (BMS).

Properties

T 271 days, emitting gamma and x-rays.

Derivative

Combination of 57Co and 58Co labelled Vitamin B12.

Nomenclature

Dicopac (Amersham).

Therapeutic Category

Diagnostic aid (pernicious anemia).

Keywords

Diagnostic Aid