12-00626. Amphotalide [Archived]

Nomenclature

CAS number: 1673-06-9
2-[5-(4-Aminophenoxy)pentyl]-1H-isoindole-1,3(2H)-dione; N-[5-(p-aminophenoxy)pentyl]phthalimide; 1-p-aminophenoxy-5-phthalimidopentane; amphothalide; RP-6171; Schistomide (Specia).
C19H20N2O3; mol wt 324.37.
C 70.35%, H 6.21%, N 8.64%, O 14.80%.

Description and references

Prepn: Ashley et al., J. Chem. Soc. 1959, 3880; Barber et al., GB 769706 (1957 to May & Baker).

Chemical structure

Properties

Crystals from ethanol, mp 113-114°.

Therapeutic Category

Anthelmintic (Schistosoma).

Keywords

Anthelmintic (Schistosoma)

Status

This monograph has been retired and is no longer subject to revision or update.