12-04586. Guanacline [Archived]

Nomenclature

CAS number: 1463-28-1
[2-(3,6-Dihydro-4-methyl-1(2H)-pyridinyl)ethyl]guanidine; N-(2-guanidinoethyl)-4-methyl-Δ3-piperidine; N-(2-guanidinoethyl)-4-methyl-1,2,3,6-tetrahydropyridine; 1-(2-guanidinoethyl)-1,2,3,6-tetrahydro-4-picoline; cyclazenin; FBA-1464.
C9H18N4; mol wt 182.27.
C 59.31%, H 9.95%, N 30.74%.

Description and references

Prepn: FR M3016 (1965 to Bayer), C.A. 62, 16206b (1965).

Chemical structure

Derivative

Monosulfate.

Nomenclature

CAS number: 1562-71-6
Leron (Bayer).
C9H18N4.H2SO4; mol wt 280.34.
C 38.56%, H 7.19%, N 19.99%, S 11.44%, O 22.83%.

Properties

Crystals from ethanol + ethyl acetate, dec 185-186°. Unstable in air.

Derivative

Neutral sulfate.

Properties

Crystals, mp 232.5°. Stable in air.

Therapeutic Category

Antihypertensive.

Keywords

Antihypertensive; Guanidine Derivatives

Status

This monograph has been retired and is no longer subject to revision or update.