Alcoholic Iodine Solution

Definition

Alcoholic Iodine Solution is a cutaneous solution.

Extemporaneous preparation

The following directions apply.

Dissolve the Potassium Iodide and the Iodine in the Purified Water and add sufficient Ethanol (90 per cent) to produce 1000 mL.

Content of iodine, I

2.4 to 2.7% w/v.

Content of potassium iodide, KI

2.4 to 2.7% w/v.

Ethanol content

83 to 88% v/v, Appendix VIII F.

Assay

For iodine

Dilute 10 mL with 20 mL of water and titrate with 0.1m sodium thiosulfate VS. Each mL of 0.1m sodium thiosulfate VS is equivalent to 12.69 mg of I.

For potassium iodide

To 10 mL add 30 mL of water and 50 mL of hydrochloric acid and titrate with 0.05m potassium iodate VS until the dark brown solution which is produced becomes pale brown. Add 1 mL of amaranth solution and continue the titration until the red colour just changes to pale yellow. From the number of mL of 0.05m potassium iodate VS required subtract half the number of mL of 0.1m sodium thiosulfate VS required in the Assay for iodine. Each mL of the remainder is equivalent to 16.60 mg of KI.

Storage

Alcoholic Iodine Solution should be kept in a well-closed container, the materials of which are resistant to iodine.

When iodine tincture is prescribed or demanded Alcoholic Iodine Solution shall be dispensed or supplied.