2595. Crotethamide

Nomenclature

CAS number: 6168-76-9
N-[1-[(Dimethylamino)carbonyl]propyl]-N-ethyl-2-butenamide; N-(1-dimethylcarbamoylpropyl)-N-ethylcrotonamide; α-(N′-crotonyl-N′-ethyl)amino-N,N-dimethylbutyramide.
C12H22N2O2; mol wt 226.32.
C 63.68%, H 9.80%, N 12.38%, O 14.14%.

Description and references

Prepn: Martin, Gysin, US 2447587 (1948 to Geigy).

Chemical structure

Properties

Liquid, bp0.03 132-134°. Easily sol in water, ether.

Derivative

Combination with cropropamide see Cropropamide.

Therapeutic Category

Combination as respiratory stimulant.

Keywords

Respiratory Stimulant