7457. Pipebuzone

Nomenclature

CAS number: 27315-91-9
4-Butyl-4-[(4-methyl-1-piperazinyl)methyl]-1,2-diphenyl-3,5-pyrazolidinedione; 1,2-diphenyl-3,5-dioxo-4-[(4-methyl-1-piperazinyl)methyl]-4-butylpyrazolidine; LD-4644; Elarzone (Alcon).
C25H32N4O2; mol wt 420.55.
C 71.40%, H 7.67%, N 13.32%, O 7.61%.

Description and references

The 4-[(4-methyl-1-piperazinyl)methyl]- deriv of phenylbutazone, q.v. Prepn: DE 1958722 and FR M7914 (both 1970 to Dausse), C.A. 73, 25460v (1970); 76, 140797j (1972).

Chemical structure

Properties

Crystals from isopropanol, mp 129°.

Therapeutic Category

Anti-inflammatory.