Therapeutic Category: Antineoplastic

Alkaloids/Natural Products

Camptothecin Derivatives

• 9-Aminocamptothecin
• Belotecan
• Exatecan
• Irinotecan
• Rubitecan
• Topotecan

Podophyllum Derivatives

• Etoposide
• Teniposide

Staurosporine Derivatives

• Enzastaurin
• Midostaurin

Taxanes

• Docetaxel
• Paclitaxel
• Paclitaxel Poliglumex

Vinca Alkaloids

• Vinblastine
• Vincristine
• Vindesine
• Vinflunine
• Vinorelbine

Others

• Aplidine
• Elliptinium Acetate
• Irofulven
• Ixabepilone
• Kahalalide F
• Trabectedin see Ecteinascidins

Alkylating Agents

Alkyl Sulfonates

• Busulfan
• Improsulfan
• Piposulfan

Aziridines

• Carboquone
• Diaziquone
• Uredepa

Ethylenimines and Methylmelamines

• Altretamine
• Triethylenemelamine
• Triethylenephosphoramide
• Triethylenethiophosphoramide

Nitrogen Mustards

• Bendamustine
• Canfosfamide
• Chlorambucil
• Chlornaphazine
• Cyclophosphamide
• Estramustine
• Glufosfamide
• Ifosfamide
• Mechlorethamine
• Mechlorethamine Oxide Hydrochloride
• Melphalan
• Perfosfamide
• Prednimustine
• Trichlormethine
• Trofosfamide
• Uracil Mustard

Nitrosoureas

• Carmustine
• Chlorozotocin
• Fotemustine
• Lomustine
• Nimustine
• Ranimustine

Others

• Dacarbazine
• Etoglucid
• Laromustine
• Mitobronitol
• Mitolactol
• Pipobroman
• Procarbazine
• Temozolomide

Antibiotics and Analogs

Actinomycins

• Cactinomycin
• Dactinomycin

Anthracyclines

• Aclacinomycins
• Amrubicin
• Carubicin
• Daunorubicin
• Doxorubicin
• Epirubicin
• Idarubicin
• Pirarubicin
• Valrubicin
• Zorubicin

Others

• Bleomycins
• Eribulin
• Mitomycins
• Peplomycin
• Plicamycin
• Porfiromycin
• Streptozocin
• Temsirolimus
• Zinostatin

Antimetabolites

Folic Acid Analogs/Antagonists

• Aminopterin
• Denopterin
• Edatrexate
• Methotrexate
• Nolatrexed
• Pemetrexed
• Piritrexim
• Pteropterin
• Raltitrexed
• Trimetrexate

Purine Analogs

• Cladribine
• Clofarabine
• Fludarabine
• 6-Mercaptopurine
• Nelarabine
• Thiamiprine
• Thioguanine
• Tiazofurin

Pyrimidine Analogs

• Ancitabine
• Azacitidine
• 6-Azauridine
• Capecitabine
• Carmofur
• Cytarabine
• Decitabine
• Doxifluridine
• Enocitabine
• Floxuridine
• Fluorouracil
• Gemcitabine
• Tegafur
• Troxacitabine

Cyclin-dependent Kinase Inhibitors

• Seliciclib

Enzymes

• Asparaginase
• Ranpirnase

Farnesyl Transferase Inhibitors

• Lonafarnib
• Tipifarnib

Histone Deacetylase Inhibitors

• Romidepsin
• Vorinostat

Immunomodulators

• Aldesleukin see Interleukin-2
• Interferon-α
• Lentinan
• Mepact
• Oregovomab
• Propagermanium
• PSK(R)
• Roquinimex
• Sipuleucel-T
• Sizofiran
• Teceleukin see Interleukin-2
• Ubenimex

Immunotoxins

• Cintredekin Besudotox
• Denileukin Diftitox

Monoclonal Antibodies

• Alemtuzumab
• Bevacizumab
• Cetuximab
• Edrecolomab
• Epratuzumab
• Gemtuzumab Ozogamicin
• Oregovomab
• Panitumumab
• Rituximab
• Tositumomab ¹³¹I see Tositumomab
• Trastuzumab

Oligonucleotides

• Agatolimod
• Aprinocarsen
• Oblimersen Sodium

Platinum Complexes

• Carboplatin
• Cisplatin
• Lobaplatin
• Oxaliplatin
• Picoplatin
• Satraplatin

Retinoids and Analogs

• Alitretinoin
• Bexarotene
• Fenretinide
• Mofarotene
• Tamibarotene

Sulfonamides

• Indisulam

Tyrosine Kinase Inhibitors

• Axitinib
• Bosutinib
• Canertinib
• Dasatinib
• Erlotinib
• Gefitinib
• Imatinib
• Lapatinib
• Motesanib
• Pazopanib
• Sorafenib
• Sunitinib
• Vandetanib
• Vatalanib

Others

• Amsacrine
• Arsenic Trioxide
• Atrasentan
• Bisantrene
• Bortezomib
• Brostallicin
• Calcitriol
• Dehydroequol
• Edotecarin
• Eflornithine
• Everolimus
• Flavopiridol
• Gallium Nitrate
• Hydroxyurea
• Liarozole
• Lonidamine
• Miltefosine
• Mitoguazone
• Mitoxantrone
• Nitracrine
• Pentostatin
• Perifosine
• Pixantrone
• Razoxane
• Seocalcitol
• Sobuzoxane
• Spirogermanium
• Tirapazamine